ClinicalTrials.gov Identifier: NCT02497014
The European Bifurcation Club Left Main Study: A Randomised Comparison of Single Versus Dual Stent Implantation for Distal Left Main True Coronary Bifurcation Lesions
Sponsor: European Cardiovascular Research Center
Percutaneous Transluminal Coronary Angioplasty
Coronary Artery Disease
Interventional Clinical Trial
Device: 1 Stent
Device: 2 Stents
Treatment of bifurcation coronary lesions remains a difficult area, in which best practice is yet to be established. This is particularly true with respect to unprotected left main stem stenting.
Whereas for non-left main bifurcation lesions there is a consensus that a single stent strategy is to be preferred where appropriate, for the left main, both the “main vessel” and the “side vessel” are main epicardial coronary arteries, and therefore of paramount importance in their own right.
Non-randomised data suggest that even in this bifurcation setting, a single stent strategy may be preferred, but these data are naturally confounded by selection bias.
We therefore plan to undertake a randomised study of left main stem true bifurcation lesions (type 1,1,1 or 0,1,1). Patients will be treated either with a planned single stent strategy or a planned dual stent strategy according to randomisation.